Research Library
PRECLINICAL

Adipotide (FTPP)

Also known as: FTPP, Prohibitin-TP01

Metabolic SignalingPeptide Signaling
ClassificationExperimental peptidomimetic designed to target the vasculature of adipose tissue.
TargetsProhibitin-targeted vasculature models; Adipose biology

Molecular Overview

Adipotide is a proapoptotic peptidomimetic studied in obesity research models for selective targeting of white-adipose vasculature.

Mechanistic Background

Homing-peptide sequence directs a proapoptotic motif to prohibitin-expressing endothelium in animal models.

What Researchers Study

Rodent and non-human-primate studies published in the early 2010s.

Evidence Landscape

Current evidence level: PRECLINICAL. Preclinical evidence does not equate to demonstrated human efficacy.

Research Limitations

Notable renal safety signals in animal studies; no human approval.

Documentation

Research Use Only

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