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Research Library
PRECLINICAL

IGF-1 DES

Also known as: DES(1-3)IGF-1

Growth Factor ResearchMuscle Biology Research
ClassificationTruncated insulin-like growth factor 1 lacking the first three N-terminal residues.
TargetsIGF-1 receptor biology; Binding-protein interaction models

Molecular Overview

DES(1-3)IGF-1 is a naturally occurring truncated IGF-1 variant with reduced binding-protein affinity, making it a common tool in receptor-signaling research.

Mechanistic Background

Reduced IGFBP binding increases free-ligand availability at the IGF-1 receptor in experimental systems.

What Researchers Study

Extensive in-vitro receptor and cell-growth literature.

Evidence Landscape

Current evidence level: PRECLINICAL. Preclinical evidence does not equate to demonstrated human efficacy.

Research Limitations

Preclinical tool compound; no approved use.

Scientific References

Documentation

Research Use Only

Molecularix Biolabs provides research materials for legitimate laboratory research. Information in this Research Library is provided for educational and scientific reference purposes and is not medical advice, treatment guidance, or a recommendation for human or veterinary use.