IGF-1 LR3
Also known as: Long R3 IGF-1, IGF-1 LR3
Molecular Overview
IGF-1 LR3 is a modified IGF-1 analog engineered with an extended N-terminus and an R3 substitution that reduces binding to IGF-binding proteins, used as a research construct to study IGF signalling.
Mechanistic Background
Reduced IGFBP binding alters IGF-1 receptor engagement in experimental systems studying IGF signalling.
What Researchers Study
Research has used LR3 constructs to probe IGF-1 receptor signalling and cellular growth pathways.
Evidence Landscape
Current evidence level: PRECLINICAL. Preclinical evidence does not equate to demonstrated human efficacy.
Research Limitations
Preclinical/laboratory research construct; human characterization limited.
Scientific References
Research Use Only
Molecularix Biolabs provides research materials for legitimate laboratory research. Information in this Research Library is provided for educational and scientific reference purposes and is not medical advice, treatment guidance, or a recommendation for human or veterinary use.